Science News – Canine and Human diseases

Researchers have found that pure bred dogs are ideal for mapping genes that cause diseases, which may help scientists understand the molecular basis for both canine and human diseases.  Almost two years ago, researchers at the Broad Institute decoded the genome of the domestic dog and they created a catalog of about 2.5 million specific genetic differences across breeds.  Due to the selective breeding of dogs over the past two centuries, scientists uncovered a genomic structure about 100 times larger than those found in the human genome. This will provide a shortcut that will allow researchers to investigate canine disease by using a few hundred animals to characterize diseases, compared to thousands of subjects that are required to study similar diseases in humans.  If you want to learn more about the work of the Broad Institute and perhaps help with their research efforts, visit dogDNA.org.

Karlsson et al. (2007) “Efficient mapping of mendelian traits in dogs through genome-wide association.” Nature Genetics DOI:10.1038/ng.2007.10

Hillbertz et al. (2007) “Duplication of FGF3, FGF4, FGF19, and ORAOV1 causes hair ridge and predisposition to dermoid sinus in Ridgeback dogs.” Nature Genetics DOI: 10.1038/ng.2007.4


Bookmark and Share
Posted: 11/15/2007 at 04:50 PM
[ ]   [ ]   [ ]   [ ]  

Posted: 11/15/2007 at 04:50 PM
[ ]   [ ]   [ ]   [ ]  

Fair Use Notice: This site contains copyrighted material the use of which has not always been
specifically authorized by the copyright owner. We are making such material
available for commentary and criticism in an efforts to advance understanding of holistic health, environmental, political, human rights, animal rights, economic, democracy, scientific, and social justice issues, etc.
We believe this constitutes a ‘fair use’ of any such copyrighted material as
provided for in section 107 of the US Copyright Law. In accordance with Title
17 U.S.C. Section 107, the material on this site is distributed without profit to
those who have expressed a prior interest in receiving the included
information for research and educational purposes. If you wish to use
copyrighted material from this site for purposes of your own that go beyond
‘fair use’, you must obtain permission from the copyright owner.


Leave a Reply

Your email address will not be published. Required fields are marked *

*

Life’s Abundance

Nature’s Sunshine

Holistic Health Journal

Reciprocal Links

Top